Neonatal thrombocytopenia as side effect of immunotherapy for recurrent spontaneous abortion.
نویسندگان
چکیده
We report a case of a 38-year-old woman with recurrent spontaneous abortion who gave birth to a thrombocytopenic neonate after immunotherapy with husband’ s leucocytes. A 38-year-old healthy female consulted the Department of Immunology and Histocompatibility Center in Thessaloniki. Medical history taken from the woman revealed two abortions. She was pregnant in 1999 and aborted at approximately 12-weeks gestational age. The second pregnancy was spontaneously aborted at approximately 8-weeks gestational age. Personal and family history of the woman were free of autoimmune or other diseases.
منابع مشابه
Effectiveness of Leukocyte Immunotherapy in Primary Recurrent Spontaneous Abortion (RSA)
Background: Recurrent spontaneous abortion (RSA) is defined as three or more se-quential abortions before the twentieth week of gestation. There are evidences to sup-port an allo-immunologic mechanism for RSA. One of the methods for treatment of RSA is leukocyte therapy; however there is still controversy about effectiveness of this method. Objectives: To evaluate the effectiveness of leukocyte...
متن کاملP-110: Evaluations of WBC Crossmatch Results After Lymphocyte Immunization in Women with Recurrent Spontaneous Abortion in Sarem Women’s Hospital
Background Recurrent spontaneous abortion (RSA) is a complication in pregnancy that results into fetus rejection by mother and several factors such as anatomical, genetic and immunological problems can be its etiologic causes. Paternal lymphocyte therapy as an immunotherapy for these patients has been more evaluated. The purpose of lymphocyte therapy is stimulation of the mother immune system t...
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متن کامل
P-223: Analysis of Synaptonemal Complex Gene Disorders Involving in Recurrent Spontaneous Abortion
Background: Spontaneous abortion (SAb) is the most common complication of early pregnancy. Numerous risk factors are associated with an increased risk of pregnancy loss such as: Maternally age, previous spontaneous abortion, prolonged ovulation to implantation, Gravidity, Interval Prolonged time to pregnancy, Balanced chromosomal translocations and Genetic disorders. The aim of this study was t...
متن کاملAnti-Thyroid Peroxidase and Risk of Recurrent Spontaneous Abortion
Background Approximately 2-4% of all women have recurrent spontaneous abortion (RSA); however, the cause is determined in only 50% of cases. Recent studies have shown an association between thyroid autoantibodies as a sign of thyroid autoimmunity and abortion. The aim of the present study was to determine whether circulating anti-thyroid peroxidase (anti-TPO) was associated with RSA. MaterialsA...
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عنوان ژورنال:
- American journal of reproductive immunology
دوره 57 3 شماره
صفحات -
تاریخ انتشار 2007